HIRSUTISM - Excessive Growth Of Androgen Dependent Sexual Hair

Hirsutism is the excessive growth of androgen dependent sexual hair (terminal hair) in facial and

central part of the body that worries the patient.

Hypertrichosis: Hypertrichosis connotes excessive growth of non-sexual (fetal lanugo type) hair.

Hyperandrogenism: Hyperandrogenism is a state of increased serum androgen level with or without any biological effect of hyperandrogenemia.

Virilism: Virilism is defined as the presence of any one or more of the following features—deepening of the voice, temporal balding, amenorrhea, enlargement of clitoris (clitoromegaly) and breast atrophy. It is a more severe form of androgen excess. Virilism may be due to adrenal hyperplasia or tumors of adrenal or ovary.

In female major androgens are: dehydroepiandrosterone sulphate (DHEA-S), dehydroepiandrosterone (DHEA), androstenedione, testosterone (T) and dihydrotestosterone (DHT). All androgenic activities are due to T and DHT.

Testosterone is the second most potent androgen in circulation, the first one being dihydrotestosterone normal female is 0.2–0.3 mg. Approximately, 50 percent of testosterone arises from peripheral conversion of prohormones, predominantly androstenedione. The principal sites of peripheral conversion are skin, muscle, fat, liver and lungs. The adrenal glands (z. reticularis and z. fasciculata) and ovaries (theca, stroma and granulosa) contribute approximately equal amounts (25%) to the circulatory levels of testosterone. Dehydroepiandrosterone sulphate (DHEA-S) arises exclusively from the adrenal glands while about 50 percent of DHEA is secreted from the adrenals.

Androstenedione arises from the adrenals and ovaries in equal amount. The sources of androgens in normal female are schematically depicted below. Most of testosterone (80%) in the circulation is bound to SHBG and is biologically inactive. About 19 percent is bound loosely with albumin and only 1 percent of the testosterone remains free which is biologically active. Normally total circulating testosterone level is 20–80 ng/dl. To exert a biological effect, testosterone (T) is metabolically converted in target tissues to dihydrotestosterone (DHT) by the enzyme 5α-reductase. DHT is the most potent androgen to stimulate the hair follicles and sebaceous glands (pilosebaceous unit). 3α-androstanediol glucuronide (3α-AG) is an important tissue metabolite of DHT. 3α-AG is thought to reflect the activity of the enzyme 5α-reductase at tissue level. T → (5α-reductase) → DHT → 3α-androstanediol (3α-A) → 3α-androstanediol glucuronide (3α-AG). Therefore, the biochemical marker for each androgen compartment is different. For the ovary it is testosterone; for the adrenal gland it is DHEA–S and for the periphery it is 3α–AG.

The pilosebaceous unit consists of sebaceous glands and hair follicles. Both are sensitive to androgens. The sebaceous glands are more sensitive to androgens than the hair follicles. Hyperstimulation of the sebaceous glands leads first to oily skin and subsequent infection results in acne. The skin and hair follicle play an active role in serving as target organs for the androgens and also in producing androgens from circulatory prohormones.

The stimulus for the excessive hair growth is testosterone. Testosterone binds to the androgen receptors in the hair follicle. This is followed by activation of the enzyme 5α-reductase. This will convert testosterone to most potent androgen—dihydrotestosterone (DHT) and androstenediol which stimulate proliferation and growth of terminal hair (anagen phase). Once the black terminal hair is produced,

Natural Ways to Cure Soft Erection

A soft erection is a form of erectile dysfunction that is defined as the inability to sustain an erection robust enough to last a few minutes during sexual intercourse. This health disorder is caused by damaged reproductive tissues and weakness in nervous function. Additionally, damaged or blocked nerves and blood vessels restrict blood supply to the reproductive tissues and cause soft erection. This health disorder is a major cause of impotence in men. Additionally, it has adverse side effects such as, lack of sexual satisfaction to you and your partner. 

Do you suffer from soft erection? Well, there are natural ways that can harden or cure your soft erection and save your relationship. 

Herbal products are considered the best natural way of curing soft erection. 4T Plus, Shilajit and Mast Mood oil are some of the best herbal products that can that efficiently cure this disorder with little side effects. 4TP Plus capsule contains natural aphrodisiacs as well as essential nutrients that help to one develop a harder erection and maintain a fuller erection during sex. Moreover, 4T Plus capsule boosts sperm concentration, semen load and remedy the disorder effectively. 

Massaging the male genitals with herbal supplements is another effective natural way to cure a soft erection. Mast Mood oil, which contains powerful herbs; tongkat ali (Eurycoma longifolia) and girji, is applied and gently massaged on to the male organs. Consistent utilization of this herbal oil stimulates cell production consequently elevating the length and thickness of the male organs. Moreover, it helps to repair damaged blood vessels and eradicates blocks that restrict blood supply to the male organs. Mast Mood oil has been used for many years to naturally cure erectile dysfunctions and boost the efficiency of the male reproductive organs during sex.

Change your diet and exercise regularly. Diet and exercise are significant in keeping fit and healthy. As said earlier, soft erection is significantly caused by anomalous vascular activities resulted from narrowed blood vessels. Avoid foods with high cholesterol levels and include bananas, avocados, carrots and sea foods in your daily diet. Practicing exercise such as yoga will significantly reduce excess fats at your lower abdomen and torso; it inhibits thickening of blood vessels.

Finally, change your lifestyle. Unhealthy practices such as smoking, abuse of recreation drugs and excessive drinking reduces your sexual fitness. Manage stress, get ample sleep and avoid utilization of sexual stimulants prior to intercourse. The discussed natural techniques to cure soft erection have little or no adverse side effects. It is time to save your relationship.

What are the Safest Sex Practices?

While many people will argue that safe sex takes all the fun out of sex, the fact is that communication with your partner and using safe sex practices will help improve your sex life by improving your relationship with your partner, and will help prevent the transmission of various STD’s. If you or your partner do have STD’s including HIV, there are a number of things that you can do to prevent the spread of these diseases.

The safest sex is to actually not have sex at all. Next to that, the safest sex is that between two partners who do not have any STD’s, who do not use injectable drugs, and who are not having sex with anyone else. If you are not sure of your partner’s sexual history or you know that there is a risk of the transferring of STD’s, there are a number of things that you can do.

Non-Penetrative Sexual Encounters

Outside of actual penetrative sex, there are a number of ways to achieve sexual satisfaction with a partner that will avoid the risk of transmitting various STD’s. These include fantasizing, phone sex, self-masturbation, mutual masturbation, sensual massage, and kissing. These encounters, especially when used together, can often achieve the same level of sexual pleasure as actual penetrative sex, but without the risks.

Safer Sexual Practices

When choosing to have penetrative sex with your partner, it’s best to do so in the safest way possible. Keep in mind that there’s no such thing as 100% safe sexual practices, but it is important to do all that you can to reduce your risks of STD’s and HIV. Safer sexual practices involve avoiding contact with your partners bodily fluids. The semen or vaginal secretions of your partner should not come into contact with your penis, vagina, anus, or mouth.

It is also important to avoid skin-to-skin contact of genitals, and to take additional precautions if you or your partner have any open sores, cuts, or wounds as any contact with these greatly increase the risk of spreading HIV. To practice safer sex, be sure to always use some type of barrier when having penetrative sex. Usually, that means using a latex male condom, but there are a number of other options available today.

Using Condoms for Safer Sex

While male condoms are most commonly used, there are also female condoms which fit inside the vagina, although these are more expensive and can be difficult to learn how to use. Either way, be sure to use latex condoms that are specifically designed to prevent disease which you can buy in drug stores and many other locations without needing a prescription.

Use a new barrier every time you have sex, and be sure to use lubricants that are water-based. Oil- and petroleum-based lubricants can cause latex condoms to break during use which renders them useless. You should also be checking condoms before using them to make sure that they appear normal. Never use a condom that feels brittle or sticky, is discolored, or has damaged packaging.